NociWise helps biotech, CROs, and clinical teams de-risk pain programs by tightening the chain from target and mechanism to models, biomarkers, endpoints, and go/no-go decisions.
Domain: nociwise.com · Remote-friendly from Dallas–Fort Worth, TX
NociWise combines deep pain neurobiology with pragmatic trial and program design—so your team gets clearer signals, tighter rationale, and cleaner decisions.
From mechanism to go/no-go
Align targets, models, biomarkers, and endpoints into a coherent translational narrative that stands up to investor, internal, and regulatory scrutiny.
Endpoint & signal optimization
Stress-test your protocol for feasibility, noise, and credibility: inclusion/exclusion, endpoints, measurement schedules, and operational risks.
Mechanism-linked readouts
Design biomarker and assay strategies that reflect the biology of your program and support translational claims.
Each package is scoped around specific deliverables and timelines. Pricing is tailored to complexity and urgency.
10–14 days · fixed scope
Tighten your pain/analgesia program from mechanism to decision gates.
Ideal before major internal reviews, financing, or partnering discussions.
5–10 days · one-time review
A focused scientific and operational review of a pain trial protocol.
Works well for sponsor, CRO, and academic-led pain trials.
5–12 days · dataset-based
Turn complex experimental data into clear figures and a coherent scientific narrative.
For internal decks, manuscripts, or partnering materials.
Retainer-based advisory support (e.g., monthly office hours and ad hoc reviews) is available for select teams. Contact us to discuss fit and availability.
NociWise is led by a translational pain scientist with postdoctoral experience in anesthesiology and pain management, combining mechanistic insight with hands-on work in models, assays, and analysis.
Expertise across pain neurobiology, nociceptor signaling, and translational models, including:
Every engagement is built around:
NociWise typically partners with:
If you work in nociception, analgesia, or pain-related targets, NociWise can help sharpen the path from data to decision.
Share a brief overview of your program, where you are in development, and what decisions are coming up. You’ll receive a short reply outlining whether and how NociWise can help.
Email: hello@nociwise.com
Location: Dallas–Fort Worth, Texas (remote-friendly)
Typical response time: 2–3 business days. Please avoid including confidential or patient-identifying information in your initial note.